Samples of biological origin include lots of contaminants. Even expensive equipment fails to remove these impurities resulting in contaminated samples being passed on for further HPLC and MS analysis.
Traditional sample preparation methods are troublesome: they often require manual work and several steps of processing, such as centrifugation, salting out or filtration.
This results in high maintenance costs. HPLC columns must often be replaced. Mass Spectrometers require expensive servicing. The whole industry got used to that because there was no better solution.
Sample pre-processing not only consumes resources but also takes time. There are no effective sample purification techniques that offer higher degree of automation.
The whole sample preparation process is fully automated. All you need to do is insert the tray with input samples, load the TLC plate and choose the appropriate program.
You can use raw samples of blood, urine, plasma, serum, saliva, soil or surface waters, skipping the initial processing. Just add the internal standard and you are ready to go.
SMR-100 uses cheap chromatographic plates, where up to 80 samples can be applied at one time. This allows to cut the cost of supplies by up to 15x compared to standard SPE columns.
The patent-pending Solvent Front Position Extraction (SFPE) technology enabled us to design a device that can process up to 60 samples an hour.
Extend the lifespan of expensive LCMS equipment and cut the maintenance costs - for example, extend the longevity of HPLC columns by up to 4 times.
Fresh Chromato introduces a new sample preparation method that enables you to extract only key components from raw samples with complicated biological matrices.
In this study, the new technique was used for isolation and determination of 7 coccidiostats, from both main groups: ionophores and chemical coccidiostats.
Its effectiveness was evaluated by comparing it with SPE-LC-MS/MS.
Validation parameters met regulatory requirements.
In many use cases, automation is not as important as ease of use, convenience and affordability! We have developed this mechanical TLC Plate Extractor as a side project to support fellow scientists' research initiatives.
Learn MoreFresh Chromato was founded by Prof. Tadeusz Dzido, previously head of Physical Chemistry Deptartment at Medical University of Lublin, Poland, along with his son Tomasz, a tech product designer.
In 1991, Prof. Dzido designed & launched the production of the first horizontal chambers for TLC, still preferred by many scientists and sold largely unchanged for over 30 years. Now, his team is giving the classic TLC technique a new life by releasing the world's most selective, fully-automated sample preparation robot.
Co-founder, Professor of Chemistry & inventor with over 40 patents.
Pioneer of research in planar and orthogonal electrochromatography.
Loves chess & fishing.
Co-founder, product designer with over 15 years of experience in the software industry. Enjoys building simple, user-friendly products that solve complex problems. Traveler at heart.
Machinery expert who once decided that fixing machines is not challening enough and started building new ones. He designs our electronics and supports construction initiatives.
Hardware designer. Visualizes & prototypes solutions for laboratory testing. Responsible for most of mechanical work on our TLC plate extractor. Breakneck downhill passionate.
Senior programmer with years of experience from the automotive industry. Does embedded programming, but also back-end and front-end development. Relentless swimmer.
SFPE sp. z o.o., VAT ID: 7123385917
Podchorążych 40/3, 20-811 Lublin, Poland
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