Tired of scraping the adsorbent layer off the chromatographic plate?
We may have just the right solution for you!

The device represents a simplified approach to extracting substances from a chromatographic plate. It uses inexpensive, disposable extraction sleeves that are designed in such a way that, under appropriate pressure, they pierce the adsorbent layer and adhere tightly to the supporting glass.

The solvent is introduced into the sleeve. After a few minutes, the solution can be collected, filtered if necessary, and sent for LC-MS analysis.

With this device, you will achieve similar results as you would with much more expensive systems. However, the TLC Plate Extractor from Fresh Chromato is quicker to set up, easier to use, and it uses as low as 50-200 µl of solvent, being not only more environmentally friendly but also producing higher concentration of analytes.

The Extration Process in Simple Steps

1. Load the chromatographic plate and use the scale on the base of the device to position it appropriately.

2. Use the supplied scissors to conveniently grab and load the sleeve into the extraction head.

3. Pull the lever to press the sleeve against the adsorbent layer. Then introduce the solvent into the sleeve. (In most cases, several tens to several hundred microliters will be enough.)

Wait a few minutes for the extraction to complete. You can aid this process by withdrawing the liquid from the sleeve and releasing it several times.

Depending on how you collect the extract at the end, you may need to filter it before loading into a vial just to make sure that no particles from the adsorbent layer are passed for LC-MS analysis.

References

The TLC Plate Extractor was tested by the scientists from Lublin Medical University, Poland. The results have been presented at the 27th International Symposium on Separation Sciences (ISSS 2023). For more information, the symposium poster can be downloaded here.

How to Order

• Use the contact form to tell us your location and whether you prefer the version for 10x10 or 20x20 cm TLC plates.
• We will get back to you with prices and delivery time.